Neuron Growth, or neurogenesis, is the biological process involving the proliferation, differentiation, and survival of new neurons in the adult brain, primarily occurring in the hippocampus and certain other brain regions. This phenomenon is a key mechanism of brain plasticity, essential for learning, memory consolidation, and adaptation to stress. Promoting robust neuron growth is a central strategy in neurological and cognitive health optimization.
Origin
Historically, it was believed that the adult brain could not generate new neurons; however, research in the late 20th century confirmed the existence of adult neurogenesis. In the hormonal health domain, the concept is critical because numerous endocrine factors and peptides, such as Brain-Derived Neurotrophic Factor (BDNF), Growth Hormone, and IGF-1, are potent regulators of this process. The term highlights the dynamic, regenerative capacity of the nervous system.
Mechanism
The process is regulated at the molecular level by neurotrophic factors and hormonal signaling that stimulate neural stem cells to divide and mature into functional neurons. BDNF, for example, acts via the TrkB receptor to promote cell survival and synaptic function. Exercise and caloric restriction are known physiological stimuli that increase BDNF production. Optimizing the hormonal milieu, including maintaining healthy levels of thyroid hormones and avoiding excessive glucocorticoid exposure, is essential to sustain the intricate pathway of neuron proliferation and integration.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.