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Neuromuscular Junction

Meaning

The highly specialized synapse, or point of chemical communication, between a motor neuron’s axon terminal and a skeletal muscle fiber, serving as the critical interface for transmitting nerve impulses to initiate muscle contraction. This junction’s structural integrity and signaling efficiency are essential for maintaining muscle strength, coordination, and functional mobility. Age-related degradation of this structure, known as sarcopenia, significantly contributes to functional decline.