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Neuromodulatory Factor Upregulation

Meaning

The targeted therapeutic strategy of enhancing the endogenous production or signaling of key regulatory peptides and proteins, such as Brain-Derived Neurotrophic Factor (BDNF), that precisely govern the excitability, plasticity, and ongoing development of neuronal circuits. Upregulation of these vital factors is essential for actively promoting neurogenesis, improving synaptic function, and significantly increasing the overall cognitive reserve. This is a vital, proactive mechanism for resisting and reversing age-related neurological decline and maintaining cognitive vitality.