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Neuromodulator Signaling Integrity

Meaning

Neuromodulator Signaling Integrity describes the optimal synthesis, release, receptor binding, and reuptake of chemical messengers that regulate the activity of large groups of neurons, influencing broad states like mood, attention, and sleep. This integrity ensures that the brain’s internal environment is stable and appropriately responsive to both internal and external stimuli, preventing functional deficits associated with neurotransmitter imbalances. It is essential for cognitive and emotional resilience.