A theoretical, clinically relevant boundary representing the maximum level of physiological or psychological demand the nervous system can effectively manage before a noticeable decline in performance, stability, or function occurs. Maintaining this threshold high and ensuring adequate distance from it is a primary goal in optimizing cognitive and emotional health. Crossing this threshold can manifest as burnout, cognitive fatigue, or heightened stress sensitivity.
Origin
The concept is derived from psychophysiology and engineering, where ‘threshold’ defines the point at which a stimulus elicits a response. In a neurological context, it relates to the excitability and metabolic capacity of neuronal networks. The term acknowledges that both metabolic reserve and neurotransmitter balance determine the brain’s functional limit.
Mechanism
The operational threshold is fundamentally determined by the efficiency of neuronal energy metabolism, the availability of key neurotransmitters, and the integrity of the blood-brain barrier. Chronic stress or hormonal imbalances, such as high circulating cortisol, can lower this threshold by depleting neurotransmitter reserves and reducing neuronal plasticity. Interventions focus on restoring metabolic reserve and balancing excitatory and inhibitory neurotransmission.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.