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Neurological Fuel Supply

Meaning

The dynamic availability and strictly regulated delivery of primary energy substrates, predominantly glucose and, secondarily, ketone bodies, across the blood-brain barrier to sustain the extraordinarily high metabolic demands of neuronal and glial cells. A consistent and balanced fuel supply is absolutely essential for maintaining optimal cognitive function, ensuring mood stability, and preventing central fatigue. Disruptions in this supply can rapidly lead to significant neurological and cognitive impairment.