A broad classification of medical conditions characterized by abnormal function in the nervous system, encompassing the brain, spinal cord, and peripheral nerves. These disorders manifest as structural, biochemical, or electrical abnormalities, leading to symptoms that affect movement, sensation, cognition, and mood. Examples include Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.
Origin
The term combines ‘neurological,’ relating to the study of the nervous system, with ‘disorders,’ signifying a state of derangement or pathological function. This classification is fundamental to the fields of neurology, psychiatry, and neuroendocrinology, establishing a framework for diagnosis.
Mechanism
The underlying mechanisms are diverse, ranging from neurodegeneration, which involves protein misfolding and neuronal death, to neuroinflammation, and autoimmune responses against neural tissue. Imbalances in neurotransmitter and hormonal signaling are also implicated, as hormones like thyroid hormones and cortisol play vital, pervasive roles in neuronal development and maintenance throughout the lifespan.
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