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Neuroinflammation Attenuation

Meaning

Neuroinflammation attenuation is the clinical and physiological process of reducing or dampening the inflammatory response within the central nervous system, which includes the brain and spinal cord. Chronic, low-grade neuroinflammation is implicated in the pathogenesis of various neurodegenerative disorders, mood disturbances, and cognitive decline. Therapeutic strategies aimed at attenuation seek to protect neuronal integrity and restore normal brain function by modulating the activity of glial cells, such as microglia and astrocytes. Hormonal balance, particularly the influence of sex steroids, can significantly impact this attenuation process.