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Neuroimmunomodulation

Meaning

Neuroimmunomodulation is the intricate, bidirectional communication and regulatory process that occurs between the nervous system and the immune system. This physiological crosstalk allows the brain to influence immune responses via neurotransmitters and hormones, while immune cells can signal back to the brain using cytokines and other inflammatory mediators. Understanding this complex network is essential, as chronic stress or dysregulated hormonal states can profoundly impair immune function and promote systemic inflammation.