Neurogenesis Peptides refer to short chains of amino acids that act as signaling molecules specifically promoting the birth, survival, and integration of new neurons within the central nervous system, particularly in the hippocampus. These compounds are being investigated for their potential to support cognitive function and recovery from neurological insult. They represent a targeted approach to neural plasticity.
Origin
The term merges the biological process of neurogenesis, known to occur in the adult brain, with the growing field of therapeutic peptide research. These molecules are often derived from larger precursor proteins involved in neural development or repair. Their study represents an exciting frontier in restorative neuroscience.
Mechanism
These peptides typically function by binding to specific neural receptors or by modulating the activity of neurotrophic factors like BDNF or VEGF, thereby influencing gene expression related to neuronal differentiation. They can cross the blood-brain barrier, allowing direct influence on neuronal precursor cells. By enhancing the survival signaling cascades, they support the integration of new cells into existing neural circuitry.
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