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Neuroendocrine Sexual Health

Meaning

Neuroendocrine sexual health is a comprehensive clinical concept that recognizes the intricate, bidirectional regulatory relationship between the nervous system, the endocrine system, and the various facets of human sexual function and reproductive well-being. This health state is dependent on the coordinated signaling of the hypothalamic-pituitary-gonadal (HPG) axis, involving the pulsatile release of GnRH, LH, and FSH, and the subsequent gonadal production of sex steroids like testosterone and estrogen. Beyond mere hormone levels, it integrates the central nervous system’s role in libido, arousal, and psychological factors, acknowledging that sexual function is a complex neurobiological and hormonal phenomenon. Optimal neuroendocrine sexual health is a critical component of overall vitality and quality of life across the lifespan.