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Neuroendocrine Sensing

Meaning

Neuroendocrine Sensing is the specialized physiological capability of the integrated neuroendocrine system to detect, interpret, and respond to subtle changes in the internal and external environments. This process involves specialized neurons and endocrine cells that monitor circulating hormone levels, nutrient status, osmotic pressure, and stress signals. Efficient neuroendocrine sensing is critical for maintaining metabolic and hormonal homeostasis, allowing the body to mount appropriate adaptive responses to physiological challenges. A decline in this sensing acuity is a hallmark of aging and chronic metabolic dysfunction.