Skip to main content

Neuroendocrine Response

Meaning

The Neuroendocrine Response is the coordinated physiological reaction of the nervous system and the endocrine system to an internal or external stimulus, such as stress, nutrient intake, or perceived threat. This integrated communication pathway involves the rapid release of neurotransmitters alongside the slower, sustained release of hormones to maintain systemic homeostasis. A well-regulated response is crucial for adaptation and survival, while chronic dysregulation is implicated in numerous conditions, including metabolic and mood disorders. Clinical assessment often focuses on the HPA axis and the sympathetic nervous system output.