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Neuroendocrine Resilience

Meaning

Neuroendocrine Resilience is the physiological capacity of the interconnected nervous and endocrine systems to maintain, or rapidly restore, homeostatic balance in the face of chronic or acute internal and external stressors. This essential adaptive quality is characterized by the robust, appropriate, and efficient regulation of key hormonal axes, such as the hypothalamic-pituitary-adrenal (HPA) axis and the somatotropic axis. High resilience signifies an individual’s ability to effectively buffer stress, prevent allostatic overload, and avoid the cascading health consequences of prolonged hormonal dysregulation, which is crucial for long-term well-being and longevity.