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Neuroendocrine Modulation

Meaning

Neuroendocrine modulation is the intricate, bidirectional process of regulating and adjusting the interaction between the nervous system and the endocrine system to maintain physiological homeostasis and adapt to environmental changes. This dynamic interplay involves specialized neurons releasing hormones into the circulation and circulating hormones influencing neuronal activity, neurotransmitter release, and gene expression in the brain. Clinical strategies often employ neuroendocrine modulation to manage stress responses, regulate energy balance, and restore reproductive function via the hypothalamic-pituitary axes.