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Neuroendocrine Interplay

Meaning

Neuroendocrine interplay describes the dynamic, integrated, and bidirectional communication and functional collaboration between the nervous system and the endocrine system, forming a unified regulatory network throughout the body. This continuous crosstalk ensures a finely coordinated physiological response to both external environmental cues and internal metabolic states, effectively translating neural signals into hormonal adjustments and vice versa. It is the fundamental mechanism governing stress adaptation, energy homeostasis, reproductive cycles, and overall systemic resilience, demonstrating the inseparable link between cognitive and somatic health. The integrity of this interplay is crucial for maintaining systemic health and functional vitality.