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Neuroendocrine-Immune Response

Meaning

The Neuroendocrine-Immune Response describes the intricate, bidirectional communication network that connects the nervous, endocrine, and immune systems, orchestrating the body’s integrated reaction to stress, infection, and homeostasis. This complex crosstalk ensures that hormonal signals, neurotransmitters, and immune cytokines work in concert to maintain systemic balance. Clinically, understanding this response is essential for addressing conditions like chronic fatigue, autoimmune disorders, and mood dysregulation, which often stem from a disruption in this central communication axis. The health of this tripartite system is foundational to overall well-being and resilience.