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Neuroendocrine Feedback Control

Meaning

Neuroendocrine Feedback Control describes the intricate regulatory loops involving the nervous system and the endocrine system, primarily through the Hypothalamic-Pituitary Axis, that maintain hormonal setpoints. This control mechanism ensures that hormone levels remain within a tight operational range necessary for homeostasis. Dysfunction in this feedback loop is a common substrate for various clinical presentations, including fatigue and mood disturbances.