Neuroendocrine Coupling

Meaning

Neuroendocrine coupling describes the direct, functional interconnection and integrated communication between the nervous system and the endocrine system, which together form the body’s major regulatory architecture. This sophisticated coupling allows rapid neural signals to influence the slower, more sustained hormonal output, and hormonal feedback to modulate neural activity. It is the core mechanism by which the body coordinates its response to acute stress, regulates complex metabolic functions, and controls the reproductive axis.

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