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Neurodegenerative Waste Management

Meaning

Neurodegenerative Waste Management is the collective term for the biological processes responsible for the efficient detection, sequestration, and clearance of misfolded proteins and cellular debris within the central nervous system. This continuous housekeeping is essential for preventing the pathological accumulation of aggregates, such as amyloid plaques and neurofibrillary tangles, which are hallmarks of various neurodegenerative diseases. Effective management is a cornerstone of cognitive preservation and long-term brain health. The efficiency of this system is a major determinant of neurological resilience over time.