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Neurodegenerative Signals

Meaning

Neurodegenerative Signals are endogenous or exogenous biochemical cues that initiate, propagate, or accelerate the pathological processes leading to neuronal dysfunction, damage, and eventual cell death within the central nervous system. These signals include misfolded proteins, chronic inflammatory cytokines, oxidative stress markers, and unmanaged metabolic dysregulation, all contributing to the progression of age-related cognitive decline. Identifying and mitigating these signals is a primary focus of neuroprotective and longevity medicine.