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Neurodegenerative Pathology Marker

Meaning

A Neurodegenerative Pathology Marker is a measurable biological or physiological indicator whose presence or alteration is closely correlated with the underlying pathological processes of neurodegenerative diseases, such as abnormal protein aggregation or neuronal loss. These markers can be biochemical, like amyloid-beta or tau protein levels, or functional, such as a significant reduction in the activity of key enzymes like choline acetyltransferase. Their clinical utility lies in early diagnosis, monitoring disease progression, and assessing the efficacy of therapeutic interventions.