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Neurodegenerative Lipid Pathology

Meaning

Neurodegenerative lipid pathology describes the collection of abnormal biochemical processes involving lipids that contribute to the progressive loss of structure or function of neurons, characteristic of diseases like Alzheimer’s and Parkinson’s. This pathology often manifests as dysregulated lipid metabolism, including the accumulation of toxic lipid species, impaired lipid transport, or excessive lipid peroxidation, all of which lead to cellular dysfunction and eventual neuronal death. It represents a key area for therapeutic intervention in age-related neurological decline.