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Neurodegenerative Diseases

Meaning

Neurodegenerative diseases are a heterogeneous group of progressive, debilitating disorders characterized by the selective and irreversible loss of structure or function of neurons in the central or peripheral nervous system. These conditions, which include Alzheimer’s, Parkinson’s, and Huntington’s disease, lead to chronic and profound neurological deficits, severely impacting cognitive function, motor control, and quality of life. The underlying pathology often involves protein aggregation, mitochondrial dysfunction, and chronic neuroinflammation.