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Neurodegenerative Disease Resilience

Meaning

The intrinsic, adaptive capacity of the central nervous system to effectively resist the pathological processes that drive neurodegenerative disorders, such as Alzheimer’s and Parkinson’s disease, and to successfully maintain optimal cognitive and motor function despite the presence of age-related molecular damage. This resilience is a complex trait dependent on the brain’s structural integrity, its robust synaptic plasticity, and its efficiency in managing chronic oxidative stress and neuroinflammation. Building this neurodegenerative disease resilience is a paramount objective in preventative neurological care and comprehensive longevity strategies.