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Neurodegenerative Disease Precursors

Meaning

Neurodegenerative Disease Precursors are measurable, subclinical biochemical, structural, or functional abnormalities that precede the overt clinical diagnosis of progressive nervous system disorders like Alzheimer’s or Parkinson’s disease. These early markers include indicators of chronic neuroinflammation, accumulation of misfolded proteins, mitochondrial dysfunction in neurons, and alterations in neurotrophic factor signaling. Identifying these precursors offers a critical window for proactive intervention.