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Neurocognitive Side Effects

Meaning

Neurocognitive side effects are unintended, adverse alterations in central nervous system function that manifest as measurable disturbances in cognitive domains such as memory, executive function, attention, or mood regulation. These effects can arise as a consequence of pharmacological interventions, underlying systemic inflammation, or significant hormonal imbalances. In the context of hormonal therapy, meticulous monitoring is essential, as hormones exert profound and direct modulatory effects on various brain regions and functions.
A vibrant green, textured half-sphere juxtaposed against a white, spiky half-sphere on a light green background. This composition visually articulates the profound shift from hormonal imbalance or hypogonadism to optimal wellness achieved through Testosterone Replacement Therapy or Estrogen Optimization. It symbolizes cellular repair and metabolic health restoration in personalized medicine.
Are There Specific Nutritional or Lifestyle Interventions That Can Mitigate the Neurocognitive Side Effects of Aromatase Inhibition?

Are There Specific Nutritional or Lifestyle Interventions That Can Mitigate the Neurocognitive Side Effects of Aromatase Inhibition?

Nutritional and lifestyle strategies can support cognitive resilience by modulating neuroinflammation and optimizing brain function during aromatase inhibition.
∞ Hypothalamic-Pituitary-Gonadal Axis
∞ Neurocognitive Side Effects
∞ TRT Protocol
HRTio
August 25, 2025