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Neurochemical Triad

Meaning

The Neurochemical Triad is a conceptual grouping of three critical neurotransmitter systems—typically dopamine, norepinephrine, and serotonin—that collectively exert pervasive control over mood, motivation, cognition, and the stress response. These three monoamines are intricately interconnected, and their balanced activity is essential for psychological well-being and peak cognitive performance. Clinical practice often focuses on restoring the equilibrium within this triad to address various neuropsychiatric and hormonal health imbalances. Disruption in one component invariably affects the function of the other two, underscoring their synergistic relationship.