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Neurochemical Changes

Meaning

Neurochemical changes refer to measurable alterations in the concentration, synthesis, release, reuptake, or degradation of neurotransmitters, neuromodulators, and other signaling molecules within the nervous system. These molecular shifts directly impact neural communication and are the basis for changes in mood, cognition, behavior, and the regulation of the entire neuroendocrine system. In the context of hormonal health, fluctuations in sex steroids, thyroid hormones, and cortisol can directly induce significant neurochemical changes, affecting mental health and brain function.