A comprehensive clinical strategy focused on providing the optimal biochemical and structural environment for the central and peripheral nervous systems to function efficiently and maintain long-term resilience. This support encompasses nutritional, pharmacological, and behavioral interventions aimed at enhancing neurotransmission, promoting neuronal survival, and mitigating neuroinflammation and oxidative stress. It is vital for cognitive health and mood regulation.
Origin
The concept is rooted in neuroscience, neuroendocrinology, and nutritional psychiatry, recognizing the profound interplay between systemic health, hormonal balance, and brain function. The understanding that neuronal health is dependent on a steady supply of specific cofactors and protection from excitotoxicity led to the development of targeted support strategies. This approach emphasizes proactive maintenance of neural circuitry.
Mechanism
Support is achieved by mechanisms such as increasing the bioavailability of essential neurotransmitter precursors, optimizing the integrity of neuronal cell membranes through phospholipids, and enhancing cerebral circulation. Specific agents may also act to modulate the balance between excitatory and inhibitory neurotransmitters or upregulate the expression of neurotrophic factors like BDNF. The overall mechanism is to stabilize synaptic function and protect neurons from the degenerative effects of chronic stress and aging.
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