Short chains of amino acids that function as signaling molecules within the central and peripheral nervous systems, specifically selected and utilized in a clinical context to promote neurogenesis, enhance synaptic plasticity, modulate neurotransmitter balance, and protect against neuronal degradation.
Origin
The term draws from the rapidly expanding field of peptide therapeutics, focusing on molecules naturally found in the body, such as Brain-Derived Neurotrophic Factor (BDNF) mimetics or regulatory neuropeptides, that possess powerful neuromodulatory and neurotrophic properties.
Mechanism
Neuro-Supportive Peptides typically operate by binding to specific G-protein coupled receptors or tyrosine kinase receptors on neuronal and glial cells, initiating intracellular cascades that upregulate survival genes and growth factors. This targeted signaling can reduce neuroinflammation, improve mitochondrial function in neurons, and facilitate the repair of damaged neural networks, thereby supporting cognitive function and emotional well-being.
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