Skip to main content

Neuro-Steroid Hormone Synthesis

Meaning

Neuro-Steroid Hormone Synthesis is the biochemical process by which specific steroid hormones are generated de novo within the central and peripheral nervous systems, independent of classical endocrine glands like the adrenals or gonads. These locally produced hormones, such as allopregnanolone and DHEA, act as potent paracrine and autocrine regulators of neuronal excitability, mood, and cognitive function. This localized production is vital for neuroprotection and maintaining neuronal plasticity. The integrity of this synthesis pathway is essential for brain resilience.