Neuro-regulatory hormone balance refers to the precise and dynamic equilibrium between the central nervous system’s signaling molecules (neurotransmitters and neuropeptides) and the peripheral endocrine system’s hormones. This delicate balance is fundamentally maintained by the Hypothalamic-Pituitary Axis, which integrates environmental and internal signals to modulate the release of hormones that control metabolism, stress response, and reproduction. Disruptions in this system can cascade into widespread hormonal dysregulation.
Origin
This term is rooted in the interdisciplinary field of neuroendocrinology, which studies the interaction between the nervous system and the endocrine system. It emphasizes the brain’s primary role in orchestrating systemic hormonal output.
Mechanism
The mechanism involves a complex feedback loop where hypothalamic neurohormones, such as GnRH or TRH, stimulate the pituitary gland to release trophic hormones, which in turn act on peripheral endocrine glands. Peripheral hormones then feed back to the brain, influencing the activity of neuro-regulatory centers, thus ensuring adaptive and homeostatic hormonal secretion in response to physiological demands.
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