A structured set of clinical and lifestyle interventions specifically designed to shield the central and peripheral nervous systems from damage, degeneration, and functional decline. These protocols focus on mitigating factors like oxidative stress, neuroinflammation, and excitotoxicity, thereby preserving neuronal integrity and synaptic function throughout the lifespan. They are a core component of cognitive longevity strategies.
Origin
The concept arises from neurological research and preventive medicine, emphasizing the proactive defense of the brain against the known mechanisms of neurodegeneration. It represents a clinical evolution from treating established neurological disease to preemptively fortifying the nervous system. The term formalizes a holistic approach to brain health.
Mechanism
Protocols function by promoting robust cerebral blood flow, optimizing the production of neurotrophic factors such as Brain-Derived Neurotrophic Factor (BDNF), and ensuring the stability of the blood-brain barrier. Furthermore, the regulation of key endocrine signals, including thyroid and sex hormones, is paramount. These hormones provide essential trophic support and anti-inflammatory action to the neuronal environment.
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