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Neuro-Muscular Fatigue

Meaning

Neuro-Muscular Fatigue is a complex, multi-factorial reduction in the maximal force or power-generating capacity of a muscle, resulting from impairment at any point along the entire pathway from the central nervous system command to the muscle fiber contraction. This state involves both central components, such as a reduced motor drive originating from the brain and spinal cord, and peripheral components, including impaired signal transmission at the neuromuscular junction or within the muscle itself. It represents a critical physiological limiting factor in sustained, high-intensity physical performance.