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Neuro-Modulation

Meaning

Neuro-Modulation is the physiological process by which a specific subset of neurotransmitters or neuropeptides alters the activity of a large number of neurons over a longer time scale than typical fast synaptic transmission. Unlike direct, point-to-point signaling, neuromodulation adjusts the overall excitability, sensitivity, and functional state of entire neural circuits. This mechanism is crucial for regulating complex behaviors, including mood, sleep-wake cycles, appetite, and the integration of hormonal feedback. In a clinical context, interventions targeting neuro-modulation are used to restore balance in the central nervous system and improve systemic responses to stress and environmental cues.