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Neuro-Metabolic Integration

Meaning

Neuro-Metabolic Integration describes the essential, highly coordinated, and reciprocal signaling pathways that connect the nervous system with the body’s peripheral metabolic processes, including energy homeostasis, glucose regulation, and nutrient sensing. This intricate integration is critical for maintaining systemic energy balance, ensuring the brain receives adequate fuel and regulatory signals, and coordinating the body’s response to nutritional status. Dysregulation in this integrated system is a fundamental component of conditions like cerebral insulin resistance and metabolic syndrome.