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Neuro-Inflammatory Pathways

Meaning

Neuro-Inflammatory Pathways are the complex signaling cascades within the central nervous system involving the activation of resident immune cells, primarily microglia and astrocytes, in response to various stimuli, including systemic inflammation, infection, or chronic stress. While acute neuroinflammation is protective, chronic activation of these pathways is detrimental, leading to neuronal dysfunction, synaptic loss, and is implicated in numerous neurodegenerative and psychiatric conditions. Modulating these pathways is a key therapeutic goal in hormonal and brain health.