Clinical interventions designed to decrease chronic, low-grade inflammatory signaling within the central nervous system, which is implicated in cognitive decline and mood disorders.
Origin
This focus arises from integrating immunology and neuroscience, recognizing the detrimental role of activated microglia and inflammatory cytokines on neuronal health.
Mechanism
Reduction is achieved by addressing systemic drivers of inflammation, optimizing vascular integrity, and utilizing specific nutritional or pharmacological agents that modulate glial cell activation states.
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