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Neuro-Inflammation Markers

Meaning

Neuro-Inflammation Markers are a panel of biochemical signaling molecules, primarily cytokines, chemokines, and reactive oxygen species, whose elevated presence within the central nervous system indicates an active inflammatory process affecting neuronal and glial cells. Clinically, these markers, such as C-reactive protein, interleukin-6, and specific microglial activation signatures, are increasingly recognized as critical mediators linking systemic inflammation to neurodegenerative conditions and mood disorders, including depression and cognitive decline. In the hormonal health domain, they are key indicators of how chronic stress and endocrine dysregulation, particularly high cortisol and low sex hormones, translate into compromised brain health and neurobiological vulnerability. Monitoring these markers provides an objective metric for assessing the inflammatory burden on the brain.