What is the Origin of Neuro-Endocrine Signaling?

This term merges "neuro," pertaining to the nervous system, and "endocrine," relating to the internal secretion of hormones, highlighting the functional link between these two primary regulatory networks. It recognizes the pituitary and hypothalamus as key integration points.

What is the Mechanism of Neuro-Endocrine Signaling?

Hypothalamic neurons release neurohormones into the portal circulation to stimulate or inhibit the anterior pituitary, which then releases tropic hormones into the systemic circulation. This cascade effectively translates neural input, such as stress perception, into systemic endocrine adjustments affecting metabolism and reproduction.

Neuro-Endocrine Signaling

Meaning

Neuro-Endocrine Signaling describes the integrated system where the nervous system directly influences hormone release, and conversely, hormones modulate neuronal activity and behavior. This crosstalk is essential for maintaining physiological equilibrium across multiple organ systems.