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Neuro-Endocrine Sensitivity

Meaning

Neuro-endocrine sensitivity is the measure of the responsiveness and fine-tuning with which the nervous system and the endocrine system communicate and integrate various internal and external stimuli. High sensitivity implies a rapid and appropriate biological response to subtle changes in the environment or internal state, while diminished sensitivity can be a sign of hormonal resistance or neurological blunting. This dynamic interaction is central to the body’s ability to adapt to stress, regulate mood, and maintain energy homeostasis.