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Neuro-Endocrine-Immune Pathways

Meaning

The Neuro-Endocrine-Immune (NEI) Pathways represent the profoundly interconnected, bidirectional communication network that integrates the nervous system, the endocrine system, and the immune system to maintain physiological homeostasis. This intricate axis ensures that psychological stress, hormonal fluctuations, and immune challenges are rapidly and appropriately coordinated across the entire organism. For optimal hormonal health, the integrity of these pathways is paramount, as chronic stress (nervous system) can suppress thyroid function (endocrine system) and impair immune surveillance. This systemic integration is the foundation of complex physiological resilience.