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Neuro-Endocrine Feedback Loop

Meaning

The Neuro-Endocrine Feedback Loop is the fundamental, bidirectional regulatory system involving the nervous system and the endocrine system, where the output of one system controls the input of the other to maintain physiological homeostasis. This intricate communication network ensures that hormonal secretion is precisely matched to the body’s needs and that the nervous system’s function is simultaneously modulated by circulating hormone levels. Clinically, understanding this loop is paramount for diagnosing and treating conditions like chronic stress, metabolic dysfunctions, and reproductive disorders.