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Neuro-Cognitive Performance Biomarkers

Meaning

Neuro-Cognitive Performance Biomarkers are quantifiable physiological or biochemical indicators that reflect the functional state and efficiency of the central nervous system, specifically related to cognitive processes such as attention, memory, executive function, and processing speed. Examples include neurotransmitter metabolite ratios, Brain-Derived Neurotrophic Factor (BDNF) levels, specific lipid profiles in cell membranes, and objective metrics from quantitative electroencephalography (qEEG) or continuous performance tasks. Clinically, these biomarkers are used to diagnose subtle neurochemical imbalances and to monitor the efficacy of interventions aimed at enhancing brain health and performance. They provide a precise window into the neurobiological substrate of cognitive output.