Neuro-Cognitive Function Decline describes the measurable deterioration in specific domains of higher cortical processing, including memory consolidation, attention span, and psychomotor speed, often associated with aging or chronic physiological stress. This is not merely subjective forgetfulness but reflects quantifiable changes in neural network integrity. Addressing this decline is paramount for maintaining independence and quality of life.
Origin
This terminology is drawn from neuropsychology, combining ‘neuro’ (relating to the nervous system) and ‘cognitive function’ (mental processes) with ‘decline’ (a reduction in performance). Its inclusion in wellness science links systemic health to central nervous system performance.
Mechanism
Decline often correlates with reduced cerebral perfusion, limiting the delivery of oxygen and glucose required for high metabolic demand in the brain. Furthermore, chronic systemic inflammation can cross the blood-brain barrier, inducing microglial activation and contributing to synaptic pruning or neuronal stress. Insufficient neurotrophic support, potentially due to suboptimal endocrine signaling, further impairs synaptic plasticity essential for learning and maintenance.
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