Neuro-Anabolic Effects describe the growth-promoting, reparative, and structural maintenance actions exerted by specific hormones and neurotrophic factors on the central and peripheral nervous system. These effects include promoting neurite outgrowth, enhancing synaptic density, stimulating neurogenesis, and protecting neurons from degradation. Hormones exhibiting these properties are crucial for sustaining cognitive function and mood regulation.
Origin
This concept is a synthesis of “neurobiology” and “anabolism,” the metabolic process of building complex molecules from simpler ones. It emerged from research demonstrating that sex steroids and neurosteroids are not merely modulators of behavior but active trophic agents in the brain. The term emphasizes the structural and functional regeneration promoted by these compounds.
Mechanism
Key hormones, such as testosterone, estrogen, and DHEA, exert their neuro-anabolic influence by binding to specific nuclear and membrane receptors on neurons and glial cells. This binding initiates gene transcription and signaling cascades that increase the expression of growth factors like BDNF. The resulting biological actions promote the maintenance of dendritic complexity and the structural integrity necessary for robust neural communication.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.