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Neural Stem Cell Survival

Meaning

Neural Stem Cell Survival refers to the successful maintenance of viability and proliferative capacity of undifferentiated cells within neurogenic niches of the adult brain, primarily the subgranular zone of the hippocampus. The long-term persistence of these cells is a prerequisite for adult neurogenesis, the process of generating new functional neurons. Clinically, the rate of stem cell survival is a key indicator of brain resilience and the potential for structural plasticity. This process is profoundly influenced by the systemic hormonal and inflammatory environment.