Neural Resilience refers to the brain’s inherent capacity to maintain or rapidly recover functional integrity following exposure to stressors, including hormonal fluctuations or inflammatory insults. This adaptability is critical for sustained cognitive performance and emotional regulation under challenging physiological conditions. It reflects the robustness of neuronal networks.
Origin
This concept merges ‘Neural,’ pertaining to the nervous system structure, with ‘Resilience,’ meaning the ability to spring back into shape. It describes the dynamic maintenance capability of the central nervous system architecture.
Mechanism
Mechanistically, neural resilience is supported by processes like neurogenesis, synaptic plasticity, and the efficient buffering capacity of glial cells against oxidative stress. Hormones such as DHEA and certain neurosteroids can directly influence neuronal membrane stability and receptor function, thereby enhancing the network’s ability to withstand perturbations. Adequate cerebral blood flow and nutrient supply are also non-negotiable prerequisites for maintaining this resilience.
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