Neural Network Integrity describes the structural and functional coherence of neuronal connectivity within the central and peripheral nervous systems, which is profoundly influenced by the neuroendocrine milieu. This integrity underpins cognitive function, mood regulation, and efficient signal transduction throughout the body. Maintaining myelination and synaptic plasticity are key components of this assessment.
Origin
This term bridges neuroscience, referencing the interconnected web of neurons, with physiology, acknowledging that hormones act as crucial modulators of synaptic function. It reflects a systems biology approach to brain health.
Mechanism
Hormones, particularly thyroid hormones, sex steroids, and glucocorticoids, directly influence neurogenesis, synaptogenesis, and the maintenance of the blood-brain barrier integrity. For instance, optimal steroid levels support the structural scaffolding necessary for efficient neurotransmitter recycling and receptor expression. Disruption to this network often manifests as cognitive impairment or affective instability.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.